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Found 5 Enz. Inhib. hit(s) with Target = 'Sodium-dependent serotonin transporter' and Ligand = 'BDBM50127383'
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50127383(3-(4-Chloro-phenyl)-8-methyl-2-(3-phenyl-isoxazol-...)
Affinity DataKi:  220nMAssay Description:Inhibition of [3H]paroxetine binding at serotonin transporter was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50127383(3-(4-Chloro-phenyl)-8-methyl-2-(3-phenyl-isoxazol-...)
Affinity DataKi:  305nMAssay Description:Binding affinity towards serotonin transporter 5-HTT was determined using [3H]paroxetine radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50127383(3-(4-Chloro-phenyl)-8-methyl-2-(3-phenyl-isoxazol-...)
Affinity DataIC50:  504nMAssay Description:Inhibitory concentration required to inhibit serotonin transporter 5-HTT was determined by using [3H]paroxetine radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50127383(3-(4-Chloro-phenyl)-8-methyl-2-(3-phenyl-isoxazol-...)
Affinity DataIC50:  2.42E+3nMAssay Description:Binding affinity towards Serotonin transporter was determined using 5-HT [3H]paroxetine as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50127383(3-(4-Chloro-phenyl)-8-methyl-2-(3-phenyl-isoxazol-...)
Affinity DataIC50:  2.42E+3nMAssay Description:Inhibition of [3H]paroxetine binding at serotonin transporter was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed