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Found 4 Enz. Inhib. hit(s) with Target = 'Sortilin' and Ligand = 'BDBM50445042'
TargetSortilin(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM50445042(CHEMBL3098767 | US10195186, Example 7 | US9682967,...)
Affinity DataKi:  162nM IC50:  170nMpH: 7.4Assay Description:The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSortilin(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM50445042(CHEMBL3098767 | US10195186, Example 7 | US9682967,...)
Affinity DataKi:  162nMAssay Description:The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSortilin(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM50445042(CHEMBL3098767 | US10195186, Example 7 | US9682967,...)
Affinity DataIC50:  170nMAssay Description:The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSortilin(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM50445042(CHEMBL3098767 | US10195186, Example 7 | US9682967,...)
Affinity DataIC50:  170nMAssay Description:Displacement of [3H]-neurotensin from sortilin (unknown origin) incubated 30 mins prior to [3H]-neurotensin addition measured after 6 hrs by scintill...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed