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Found 2 Enz. Inhib. hit(s) with Target = 'Sphingosine 1-phosphate receptor 1' and Ligand = 'BDBM221928'
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Beijing Foreland Biopharma

US Patent
LigandPNGBDBM221928(US9315492, 29)
Affinity DataIC50:  0.400nMpH: 7.4Assay Description:Test method: wetting membranes by saponin solution, and preparing [35S]-GTPγS in binding solution (4×). The test compound was prepared as 4× of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Mus musculus (Mouse))
Beijing Foreland Biopharma

US Patent
LigandPNGBDBM221928(US9315492, 29)
Affinity DataEC50:  9.90nMT: 2°CAssay Description:Assay procedures: OCC culture solution was preheated in water tank at 37° C. Cells were taken out from liquor nitrogen tank, left on the dry-ice, and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent