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Found 2 Enz. Inhib. hit(s) with Target = 'Sphingosine 1-phosphate receptor 1' and Ligand = 'BDBM22211'
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM22211(1,2,4-oxadiazole based compound, 28 | 1-({4-[5-(4-...)
Affinity DataIC50:  5.10nMpH: 7.5 T: 2°CAssay Description:The assay measures the displacement of [33P]-labeled sphingosine-1-phosphate (S1P) by test compounds from human S1P receptors expressed on CHO cell m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM22211(1,2,4-oxadiazole based compound, 28 | 1-({4-[5-(4-...)
Affinity DataIC50:  8.53nMAssay Description:Newly synthesized compounds were first evaluated for binding potency toward S1P1 by a [32P]S1P competitive binding assay following published procedur...More data for this Ligand-Target Pair
In DepthDetails US Patent