Found 3 Enz. Inhib. hit(s) with Target = 'Sphingosine 1-phosphate receptor 1' and Ligand = 'BDBM22223'
Affinity DataEC50: 0.0800nMpH: 7.4 T: 2°CAssay Description:EC50s were determined by measuring the binding of [35S]-GTP-gamma-S to S1P receptors expressed in transfected Chinese hamster ovary (CHO) cell membr...More data for this Ligand-Target Pair
Affinity DataEC50: 0.100nMAssay Description:Agonist activity at S1P1 receptor assessed as induction of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataEC50: <0.0800nMAssay Description:Agonist activity at S1P1 receptor expressed in CHO cells measured as S1P-induced [35S]GTPgammaS uptakeMore data for this Ligand-Target Pair