Found 9 Enz. Inhib. hit(s) with Target = 'Sphingosine 1-phosphate receptor 1' and Ligand = 'BDBM50386853'
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Arena Pharmaceuticals
Curated by ChEMBL
Arena Pharmaceuticals
Curated by ChEMBL
Affinity DataEC50: 1.10nMAssay Description:Agonist activity against human S1P1 assessed as accumulation of cAMP by HTRF assayMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Arena Pharmaceuticals
Curated by ChEMBL
Arena Pharmaceuticals
Curated by ChEMBL
Affinity DataEC50: 1.10nMAssay Description:Agonist activity against human S1P1 assessed as accumulation of cAMP by HTRF assayMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Arena Pharmaceuticals
Curated by ChEMBL
Arena Pharmaceuticals
Curated by ChEMBL
Affinity DataEC50: 1.73nMAssay Description:Agonist activity against human S1P1 assessed as accumulation of cAMP by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.40nMAssay Description:Agonist activity against rat S1P1 assessed as accumulation of cAMP by HTRF assayMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Arena Pharmaceuticals
Curated by ChEMBL
Arena Pharmaceuticals
Curated by ChEMBL
Affinity DataEC50: 55nMAssay Description:Agonist activity against human S1P1 by beta arrestin recruitment assayMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 1(Mus musculus (Mouse))
Arena Pharmaceuticals
Curated by ChEMBL
Arena Pharmaceuticals
Curated by ChEMBL
Affinity DataEC50: 8.30nMAssay Description:Agonist activity against mouse S1P1 assessed as accumulation of cAMP by HTRF assayMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 1(Mus musculus (Mouse))
Arena Pharmaceuticals
Curated by ChEMBL
Arena Pharmaceuticals
Curated by ChEMBL
Affinity DataEC50: 8.30nMAssay Description:Agonist activity against mouse S1P1 assessed as accumulation of cAMP by HTRF assayMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Arena Pharmaceuticals
Curated by ChEMBL
Arena Pharmaceuticals
Curated by ChEMBL
Affinity DataEC50: 55nMAssay Description:Agonist activity against human S1P1 by beta arrestin recruitment assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.40nMAssay Description:Agonist activity against rat S1P1 assessed as accumulation of cAMP by HTRF assayMore data for this Ligand-Target Pair