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Found 9 Enz. Inhib. hit(s) with Target = 'Sphingosine 1-phosphate receptor 1' and Ligand = 'BDBM50386853'
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50386853(CHEMBL2048287)
Affinity DataEC50:  1.10nMAssay Description:Agonist activity against human S1P1 assessed as accumulation of cAMP by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50386853(CHEMBL2048287)
Affinity DataEC50:  1.10nMAssay Description:Agonist activity against human S1P1 assessed as accumulation of cAMP by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50386853(CHEMBL2048287)
Affinity DataEC50:  1.73nMAssay Description:Agonist activity against human S1P1 assessed as accumulation of cAMP by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Rattus norvegicus)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50386853(CHEMBL2048287)
Affinity DataEC50:  1.40nMAssay Description:Agonist activity against rat S1P1 assessed as accumulation of cAMP by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50386853(CHEMBL2048287)
Affinity DataEC50:  55nMAssay Description:Agonist activity against human S1P1 by beta arrestin recruitment assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Mus musculus (Mouse))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50386853(CHEMBL2048287)
Affinity DataEC50:  8.30nMAssay Description:Agonist activity against mouse S1P1 assessed as accumulation of cAMP by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Mus musculus (Mouse))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50386853(CHEMBL2048287)
Affinity DataEC50:  8.30nMAssay Description:Agonist activity against mouse S1P1 assessed as accumulation of cAMP by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50386853(CHEMBL2048287)
Affinity DataEC50:  55nMAssay Description:Agonist activity against human S1P1 by beta arrestin recruitment assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Rattus norvegicus)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50386853(CHEMBL2048287)
Affinity DataEC50:  1.40nMAssay Description:Agonist activity against rat S1P1 assessed as accumulation of cAMP by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed