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Found 3 Enz. Inhib. hit(s) with Target = 'Sphingosine 1-phosphate receptor 2' and Ligand = 'BDBM50143203'
TargetSphingosine 1-phosphate receptor 2(Homo sapiens (Human))
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50143203(CHEMBL3759434)
Affinity DataIC50:  8.20nMAssay Description:Antagonist activity at S1P2 receptor (unknown origin) expressed in CHO cells assessed as inhibition of S1P-induced increase in intracellular calcium ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 2(Homo sapiens (Human))
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50143203(CHEMBL3759434)
Affinity DataIC50:  500nMAssay Description:Displacement of [33P]-S1P from human S1P2 receptor expressed on CHO-K1 cell membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 2(Homo sapiens (Human))
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50143203(CHEMBL3759434)
Affinity DataKd:  32nMAssay Description:Binding affinity to S1PR2 (unknown origin) assessed as dissociation constant by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed