Found 5 Enz. Inhib. hit(s) with Target = 'Sphingosine 1-phosphate receptor 2' and Ligand = 'BDBM50585281'
Affinity DataIC50: 3.20nMAssay Description:Antagonist activity at human S1P2 receptor expressed in CHO cells assessed as inhibition of calcium fluxMore data for this Ligand-Target Pair
Affinity DataIC50: 3.5nMAssay Description:Antagonist activity at human S1P2 in HFL1 cells assessed as inhibition of EC80 S1P-induced IL8 release incubated for 16 to 24 hrs by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 7.70nMAssay Description:Antagonist activity against human S1P2 assessed as inhibition of beta-arrestin 2 recruitmentMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Antagonist activity at human S1P2 receptor expressed in CHO cells assessed as inhibition of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataIC50: 197nMAssay Description:Antagonist activity at human S1P2 in HFL1 cells assessed as inhibition of EC80 S1P-induced IL8 release incubated for 16 to 24 hrs in presence of 2% H...More data for this Ligand-Target Pair