Found 3 Enz. Inhib. hit(s) with Target = 'Sphingosine-1-phosphate lyase 1' and Ligand = 'BDBM50158336'
TargetSphingosine-1-phosphate lyase 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of human recombinant S1PL (62 to 568) expressed in Sf9 insect cells using S1P as substrate after 1 hrMore data for this Ligand-Target Pair
TargetSphingosine-1-phosphate lyase 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 5.20E+4nMAssay Description:Inhibition of S1PL (unknown origin)More data for this Ligand-Target Pair
TargetSphingosine-1-phosphate lyase 1(Mus musculus)
Spanish National Research Council (Csic)
Curated by ChEMBL
Spanish National Research Council (Csic)
Curated by ChEMBL
Affinity DataIC50: 5.24E+4nMAssay Description:Inhibition of mouse liver microsomal S1PL using S1P as substrate incubated for 20 mins by ESI-LC/MS analysisMore data for this Ligand-Target Pair