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Found 2 Enz. Inhib. hit(s) with Target = 'Sphingosine-1-phosphate lyase 1' and Ligand = 'BDBM65110'
TargetSphingosine-1-phosphate lyase 1(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM65110(US10166249, Example 473 | US9522888, 473)
Affinity DataIC50: <10nMAssay Description:Membranes were prepared from CHO cells expressing human S1P1. Cells pellets (1×109 cells/pellet) were suspended in buffer containing 20 mM HEPES (4-(...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSphingosine-1-phosphate lyase 1(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM65110(US10166249, Example 473 | US9522888, 473)
Affinity DataEC50:  55nMAssay Description:hS1P1/CHO cells were plated into BD Amine 384-well plates the day before the assay. On the day of the assay, growth medium was removed and replaced w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent