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Found 2 Enz. Inhib. hit(s) with Target = 'Steroid 17-alpha-hydroxylase/17,20 lyase' and Ligand = 'BDBM132127'
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
Novartis

US Patent
LigandPNGBDBM132127(USRE45173, 52A)
Affinity DataIC50:  5nMAssay Description:Cytochrome P450, 17-20 lyase (CYP17-lyase) assay development using recombinant human CYP17 enzyme and 17-alpha -hydroxy pregnenolone [21-3H] as the s...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM132127(USRE45173, 52A)
Affinity DataIC50:  96nMAssay Description:Cytochrome P450, 17-20 lyase (CYP17-lyase) assay development using recombinant human CYP17 enzyme and 17-alpha -hydroxy pregnenolone [21-3H] as the s...More data for this Ligand-Target Pair
In DepthDetails US Patent