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Found 2 Enz. Inhib. hit(s) with Target = 'Steroid 21-hydroxylase' and Ligand = 'BDBM314740'
TargetSteroid 21-hydroxylase(Homo sapiens (Human))
University of Kansas

US Patent
LigandPNGBDBM314740(US9611270, Example 42)
Affinity DataIC50:  8nMAssay Description:Complementary assays were utilized for the quantitative comparison of compound activity data for CYP17A1 and CYP21A2. Progesterone is a substrate for...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails US Patent
TargetSteroid 21-hydroxylase(Homo sapiens (Human))
University of Kansas

US Patent
LigandPNGBDBM314740(US9611270, Example 42)
Affinity DataIC50:  673nMAssay Description:Inhibition of C-terminal His-tagged recombinant human CYP21A2deltaH mutant expressed in Escherichia coli DH5alpha assessed as decrease in progesteron...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed