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Compile Data Set for Download or QSAR
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Found
1
Enz. Inhib. hit(s) with Target = 'Sterol 14-alpha demethylase' and Ligand = 'BDBM213824'
Target
Sterol 14-alpha demethylase
(Trypanosoma cruzi)
Vanderbilt University
Ligand
BDBM213824
(Posaconazole)
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Affinity Data
Kd: 18nM
pH: 7.4 T: 2°C
Assay Description:
Briefly, the reaction mixture contained 1 uM CYP51, 2 uM cytochrome P450 reductase, 100 uM dilauroyl-alpha-phosphatidylcholine, 0.4 mg/ml isoctrate d...
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