Found 2 Enz. Inhib. hit(s) with Target = 'Sterol 14-alpha demethylase' and Ligand = 'BDBM213825' TargetSterol 14-alpha demethylase(Trypanosoma cruzi)
Vanderbilt University School Of Medicine
Curated by ChEMBL
Vanderbilt University School Of Medicine
Curated by ChEMBL
Affinity DataKd: 8.30nMAssay Description:Binding affinity to Trypanosoma cruzi Y CYP51A expressed in Escherichia coliMore data for this Ligand-Target Pair
3D Structure (crystal)TargetSterol 14-alpha demethylase(Trypanosoma cruzi)
Vanderbilt University School Of Medicine
Curated by ChEMBL
Vanderbilt University School Of Medicine
Curated by ChEMBL
Affinity DataKd: 15nMpH: 7.4 T: 2°CAssay Description:Briefly, the reaction mixture contained 1 uM CYP51, 2 uM cytochrome P450 reductase, 100 uM dilauroyl-alpha-phosphatidylcholine, 0.4 mg/ml isoctrate d...More data for this Ligand-Target Pair
