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Found 3 Enz. Inhib. hit(s) with Target = 'Steryl-sulfatase' and Ligand = 'BDBM50266404'
TargetSteryl-sulfatase(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50266404(CHEMBL4102153)
Affinity DataIC50:  5.10nMAssay Description:Inhibition of STS in human T47D cells preincubated for 1 hr followed by addition of [3H]-E1S/E1S as substrate measured after 24 hrs by HPLC based rad...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50266404(CHEMBL4102153)
Affinity DataIC50:  5.70nMAssay Description:Irreversible inhibition of STS in human T47D cells preincubated for 2 hrs followed by compound washout and addition of [3H]-E1S/E1S as substrate meas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50266404(CHEMBL4102153)
Affinity DataIC50:  82nMAssay Description:Inhibition of human placental microsomal STS assessed as formation of E1 preincubated for 30 mins followed by addition of E1S as substrate measured a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed