Report error Found 9 Enz. Inhib. hit(s) with Target = 'Substance-K receptor' and Ligand = 'BDBM50001447'
Affinity DataEC50: 0.550nMAssay Description:Allosteric modulation of rat NK2 receptor expressed in HEK293 cells assessed as increase in intracellular calcium level by spectrofluorimetryMore data for this Ligand-Target Pair
Affinity DataKi: 0.710nMAssay Description:The compound was tested for competition binding with [3H]NKA against the CHO cells from cloned human Tachykinin receptor 2More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Competitive inhibition of [125I]NKA binding to hamster urinary bladder Tachykinin receptor 2More data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Displacement of [3H]GR100679 from NK2 receptor (unknown origin) expressed in CHO/T cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 1.70nMAssay Description:In vitro agonistic activity against tachykinin receptor 2 of rat colon muscularis mucosae.More data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Inhibitory activity against human Tachykinin receptor 2More data for this Ligand-Target Pair
Affinity DataIC50: 7.70nMAssay Description:Tested for the binding affinity to human NK2 receptor expressed in Sf-9 insect larval cells using 0.1 nM 2-[125 I] iodohistidyl neurokinin AMore data for this Ligand-Target Pair
Affinity DataEC50: 64.8nMAssay Description:Allosteric modulation of rat NK2 receptor expressed in HEK293 cells assessed as cAMP production by radioimmunoassayMore data for this Ligand-Target Pair
Affinity DataKi: 3.70E+3nMAssay Description:Evaluated for the binding affinity against NK2 receptorMore data for this Ligand-Target Pair
