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Found 6 Enz. Inhib. hit(s) with Target = 'Substance-P receptor' and Ligand = 'BDBM50034271'
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50034271(4-(3,5-Bis-trifluoromethyl-benzyloxymethyl)-4-phen...)
Affinity DataIC50:  0.950nMAssay Description:Antagonistic activity against human Tachykinin receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50034271(4-(3,5-Bis-trifluoromethyl-benzyloxymethyl)-4-phen...)
Affinity DataIC50:  0.950nMAssay Description:Binding affinity at human tachykinin receptor 1 by measuring its ability to displace [125I]-labeled substance P from the cloned receptor expressed in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50034271(4-(3,5-Bis-trifluoromethyl-benzyloxymethyl)-4-phen...)
Affinity DataIC50:  0.950nMAssay Description:Displacement of [125I]-labeled substance P from the cloned Tachykinin receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50034271(4-(3,5-Bis-trifluoromethyl-benzyloxymethyl)-4-phen...)
Affinity DataIC50:  0.955nMAssay Description:Binding affinity was measured against the Tachykinin receptor 1 in CHO-expressed hNK1 using [125I]SP.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50034271(4-(3,5-Bis-trifluoromethyl-benzyloxymethyl)-4-phen...)
Affinity DataIC50:  1nMAssay Description:Inhibition of substance P binding to Tachykinin receptor 1 in Chinese hamster ovary cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50034271(4-(3,5-Bis-trifluoromethyl-benzyloxymethyl)-4-phen...)
Affinity DataIC50:  1nMAssay Description:Displacement of [125I]substance P from human recombinant NK1 receptor expressed in human U373 cells after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed