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Found 5 Enz. Inhib. hit(s) with Target = 'Substance-P receptor' and Ligand = 'BDBM50067935'
TargetSubstance-P receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50067935((2-Methoxy-5-trifluoromethoxy-benzyl)-((2S,3S)-2-p...)
Affinity DataIC50:  0.0120nMAssay Description:Displacement of [125I]BH-SP from NK1 receptor in human IM9 cells after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50067935((2-Methoxy-5-trifluoromethoxy-benzyl)-((2S,3S)-2-p...)
Affinity DataIC50:  0.140nMAssay Description:Displacement of [125I]-labeled SP from the human Tachykinin receptor 1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50067935((2-Methoxy-5-trifluoromethoxy-benzyl)-((2S,3S)-2-p...)
Affinity DataIC50:  0.140nMAssay Description:Displacement of [125I]-labelled substance P from cloned human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50067935((2-Methoxy-5-trifluoromethoxy-benzyl)-((2S,3S)-2-p...)
Affinity DataIC50:  0.190nMAssay Description:Antagonist activity for Tachykinin receptor 1 as displacement of [3H]-Substance P in human IM-9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50067935((2-Methoxy-5-trifluoromethoxy-benzyl)-((2S,3S)-2-p...)
Affinity DataIC50:  0.400nMAssay Description:Displacement of [3H]spiperone from NK1 receptor in human IM9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed