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Found 2 Enz. Inhib. hit(s) with Target = 'TGF-beta receptor type-1 [162-503]' and Ligand = 'BDBM451799'
TargetTGF-beta receptor type-1 [162-503](Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM451799(2-amino-N-((1r,4R)-4-hydroxycyclohexyl)-5-(4-(((R)...)
Affinity DataIC50:  3.50E+3nMAssay Description:A kinase selectivity panel which measures substrate peptide phosphorylation was set-up for wild-type ALK2 (aa172-499), ALK2 FOP mutant (aa172-499 R20...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTGF-beta receptor type-1 [162-503](Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM451799(2-amino-N-((1r,4R)-4-hydroxycyclohexyl)-5-(4-(((R)...)
Affinity DataIC50:  3.50E+3nMAssay Description:In the applied method, this separation takes place inside a chip that contains a complex capillary system for simultaneous analysis of 12 samples (“1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent