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Found 2 Enz. Inhib. hit(s) with Target = 'TGF-beta receptor type-2' and Ligand = 'BDBM406696'
TargetTGF-beta receptor type-2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM406696(N-[2-(pyridin-2-yl)pyrrolo[2,1-f][1,2,4]triazin-4-...)
Affinity DataIC50:  77nMAssay Description:Inhibition of wild type His-tagged TGFbetaR2 (unknown origin) after 1 hr by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM406696(N-[2-(pyridin-2-yl)pyrrolo[2,1-f][1,2,4]triazin-4-...)
Affinity DataIC50:  80nMAssay Description:Assays are conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or HIS-TGFβR2 WT, anti-HIS detec...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent