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Found 14 Enz. Inhib. hit(s) with Target = 'Telomerase reverse transcriptase' and Ligand = 'BDBM50105463'
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Anhui Medical University

Curated by ChEMBL
LigandPNGBDBM50105463(2,7-diamino-10-ethyl-9-phenylphenanthridinium brom...)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of telomerase in human MGC803 cell extracts after 24 hrs by TRAP-PCR-ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Anhui Medical University

Curated by ChEMBL
LigandPNGBDBM50105463(2,7-diamino-10-ethyl-9-phenylphenanthridinium brom...)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of telomerase in human MGC803 cells after 24 hrs by TRAP-PCR-ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Anhui Medical University

Curated by ChEMBL
LigandPNGBDBM50105463(2,7-diamino-10-ethyl-9-phenylphenanthridinium brom...)
Affinity DataIC50:  2.16E+3nMAssay Description:Inhibition of telomerase activity in human CNE-2 cellsMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Anhui Medical University

Curated by ChEMBL
LigandPNGBDBM50105463(2,7-diamino-10-ethyl-9-phenylphenanthridinium brom...)
Affinity DataIC50:  2.18E+3nMAssay Description:Inhibition of telomerase in human MGC803 cells after 24 hrs by TRAP-PCR-ELISA methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Anhui Medical University

Curated by ChEMBL
LigandPNGBDBM50105463(2,7-diamino-10-ethyl-9-phenylphenanthridinium brom...)
Affinity DataIC50:  2.33E+3nMAssay Description:Inhibition of telomerase in human MDA-MB-231 cells after 24 hrs by TRAP-PCR-ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Anhui Medical University

Curated by ChEMBL
LigandPNGBDBM50105463(2,7-diamino-10-ethyl-9-phenylphenanthridinium brom...)
Affinity DataIC50:  2.39E+3nMAssay Description:Inhibition of telomerase-mediated supercoiling activity in human MGC803 cells after 24 hrs by TRAP-PCR-ELISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Anhui Medical University

Curated by ChEMBL
LigandPNGBDBM50105463(2,7-diamino-10-ethyl-9-phenylphenanthridinium brom...)
Affinity DataIC50:  2.47E+3nMAssay Description:Inhibition of telomerase supercoiling activity in human MGC803 cells after 24 hrs by TRAP-PCR-ELISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Anhui Medical University

Curated by ChEMBL
LigandPNGBDBM50105463(2,7-diamino-10-ethyl-9-phenylphenanthridinium brom...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of telomerase in human SGC7901 cells by TRAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Anhui Medical University

Curated by ChEMBL
LigandPNGBDBM50105463(2,7-diamino-10-ethyl-9-phenylphenanthridinium brom...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of telomerase in human SGC7901 cells by TRAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Anhui Medical University

Curated by ChEMBL
LigandPNGBDBM50105463(2,7-diamino-10-ethyl-9-phenylphenanthridinium brom...)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of telomerase in human SGC7901 cells by TRAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Anhui Medical University

Curated by ChEMBL
LigandPNGBDBM50105463(2,7-diamino-10-ethyl-9-phenylphenanthridinium brom...)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of telomerase activity expressed in human SGC7901 cells by SYBER green dye based TRAPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Anhui Medical University

Curated by ChEMBL
LigandPNGBDBM50105463(2,7-diamino-10-ethyl-9-phenylphenanthridinium brom...)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibitory activity of the compound against telomerase (Compound released from RNA/DNA heteroduplex derivatized resin [sequence (TTAGGG)3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Anhui Medical University

Curated by ChEMBL
LigandPNGBDBM50105463(2,7-diamino-10-ethyl-9-phenylphenanthridinium brom...)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibitory activity of the compound against telomerase (Compound released from underivatized resinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Anhui Medical University

Curated by ChEMBL
LigandPNGBDBM50105463(2,7-diamino-10-ethyl-9-phenylphenanthridinium brom...)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibitory activity of the compound against telomerase (Compound released from DNA/DNA heteroduplex derivatized resin [sequence (TTAGGG)3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed