Found 12 Enz. Inhib. hit(s) with Target = 'Telomerase reverse transcriptase' and Ligand = 'BDBM50126186' TargetTelomerase reverse transcriptase(Homo sapiens (Human))
University Of California
Curated by ChEMBL
University Of California
Curated by ChEMBL
Affinity DataIC50: 93nMAssay Description:Inhibition of telomerase in human HeLa cells after 2 hrs by [alpha-32P]dGTP incorporation assayMore data for this Ligand-Target Pair
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
University Of California
Curated by ChEMBL
University Of California
Curated by ChEMBL
Affinity DataIC50: 93nMAssay Description:Inhibition of human telomerase isolated from human HeLa cells nuclear extracts expressed in insect cells assessed as [33P]dCMP incorporation after 30...More data for this Ligand-Target Pair
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
University Of California
Curated by ChEMBL
University Of California
Curated by ChEMBL
Affinity DataIC50: 93nMAssay Description:Inhibition of human telomeraseMore data for this Ligand-Target Pair
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
University Of California
Curated by ChEMBL
University Of California
Curated by ChEMBL
Affinity DataIC50: 170nMAssay Description:Inhibition of telomerase in human MDA-MB-231 cells after 24 hrs by TRAP-PCR-ELISAMore data for this Ligand-Target Pair
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
University Of California
Curated by ChEMBL
University Of California
Curated by ChEMBL
Affinity DataIC50: 280nMAssay Description:Inhibition of telomerase in human MGC803 cell extracts after 24 hrs by TRAP-PCR-ELISAMore data for this Ligand-Target Pair
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
University Of California
Curated by ChEMBL
University Of California
Curated by ChEMBL
Affinity DataIC50: 280nMAssay Description:Inhibition of telomerase in human MGC803 cells after 24 hrs by TRAP-PCR-ELISAMore data for this Ligand-Target Pair
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
University Of California
Curated by ChEMBL
University Of California
Curated by ChEMBL
Affinity DataIC50: 410nMAssay Description:Inhibition of telomerase in human MGC803 cell extracts after 24 hrs by TRAP-PCR-ELISAMore data for this Ligand-Target Pair
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
University Of California
Curated by ChEMBL
University Of California
Curated by ChEMBL
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of telomerase in human HeLa cells using 5'-AAT CCG TCG AGC AGA GTT-3' as substrate incubated for 15 mins prior to extension reaction by te...More data for this Ligand-Target Pair
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
University Of California
Curated by ChEMBL
University Of California
Curated by ChEMBL
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of human telomerase activity isolated from HEK293 cells assessed as reduction in dNTP incorporation using 5'-biotinylated AATCCGTCGAGCAGAG...More data for this Ligand-Target Pair
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
University Of California
Curated by ChEMBL
University Of California
Curated by ChEMBL
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of telomerase in human HeLa cells using 5'-AAT CCG TCG AGC AGA GTT-3' as substrate incubated for 15 mins prior to extension reaction follo...More data for this Ligand-Target Pair
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
University Of California
Curated by ChEMBL
University Of California
Curated by ChEMBL
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibitory activity of the compound against telomeraseMore data for this Ligand-Target Pair
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
University Of California
Curated by ChEMBL
University Of California
Curated by ChEMBL
Affinity DataIC50: 1.16E+4nMAssay Description:Inhibition of telomerase activity (unknown origin) in cell free system using sulforhodamine labeled primer measured after 30 mins by telomerase repea...More data for this Ligand-Target Pair
