Found 4 Enz. Inhib. hit(s) with Target = 'Thioredoxin reductase 1, cytoplasmic' and Ligand = 'BDBM50515528' TargetThioredoxin reductase 1, cytoplasmic(Rattus norvegicus)
University Of Belgrade
Curated by ChEMBL
University Of Belgrade
Curated by ChEMBL
Affinity DataIC50: 600nMAssay Description:Inhibition of rat TrxR1 using DTNB as substrate preincubated for 15 mins followed by substrate addition and measured for 20 mins by Ellman's methodMore data for this Ligand-Target Pair
TargetThioredoxin reductase 1, cytoplasmic(Rattus norvegicus)
University Of Belgrade
Curated by ChEMBL
University Of Belgrade
Curated by ChEMBL
Affinity DataIC50: 600nMAssay Description:Inhibition of recombinant rat TrxR1 using DTNB as substrate preincubated for 15 mins followed by substrate addition and measured for 20 mins by color...More data for this Ligand-Target Pair
TargetThioredoxin reductase 1, cytoplasmic(Homo sapiens (Human))
University Of Belgrade
Curated by ChEMBL
University Of Belgrade
Curated by ChEMBL
Affinity DataIC50: 960nMAssay Description:Inhibition of TrxR1 (unknown origin) using DTNB as substrate preincubated for 30 mins in presence of insulin followed by substrate addition by colori...More data for this Ligand-Target Pair
TargetThioredoxin reductase 1, cytoplasmic(Homo sapiens (Human))
University Of Belgrade
Curated by ChEMBL
University Of Belgrade
Curated by ChEMBL
Affinity DataIC50: 7.26E+3nMAssay Description:Inhibition of TrxR in human SH-SY5Y cells using DTNB as substrate preincubated for 15 mins followed by substrate addition and measured for 20 mins by...More data for this Ligand-Target Pair
