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Report error Found 6 Enz. Inhib. hit(s) with Target = 'Thymidine kinase, cytosolic' and Ligand = 'BDBM1'
TargetThymidine kinase, cytosolic(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM1(dT | thymidine)
Affinity DataKi:  200nMAssay Description:Binding affinity constant against HSV-1 thymidine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase, cytosolic(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM1(dT | thymidine)
Affinity DataKi:  2.00E+3nMAssay Description:Inhibition of HSV-1 thymidine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase, cytosolic(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM1(dT | thymidine)
Affinity DataIC50:  16nMAssay Description:Inhibitory activity (50 uM) against HSV-1 Thymidine kinase in OST-TK-/HSV-1 TK+ cell line in combination with BVAraUMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase, cytosolic(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM1(dT | thymidine)
Affinity DataIC50:  26nMAssay Description:Inhibitory activity (50 uM) against HSV-1 Thymidine kinase in OST-TK-/HSV-1 TK+ cell line in combination with gancicclovirMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase, cytosolic(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM1(dT | thymidine)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibitory concentration against HSV-1 TK (WT) catalyzed [3H]-GCV phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase, cytosolic(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM1(dT | thymidine)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibitory concentration against HSV-1 TK (A167Y) catalyzed [3H]-GCV phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed