Affinity DataKi: 0.0900nMAssay Description:The compound was tested for inhibitory activity against thymidylate synthase(purified recombinant human gene) from E. coliMore data for this Ligand-Target Pair
Affinity DataKi: 0.0900nMAssay Description:Inhibition of TS by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibition of Escherichia coli TS assessed as oxidation of tetrahydrofolate to dihydrofolate after 2 to 12 mins by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Inhibition of human TS assessed as oxidation of tetrahydrofolate to dihydrofolate after 2 to 12 mins by spectrophotometryMore data for this Ligand-Target Pair