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Found 2 Enz. Inhib. hit(s) with Target = 'Thymidylate synthase' and Ligand = 'BDBM50590309'
TargetThymidylate synthase(Homo sapiens (Human))
University Of Modena And Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50590309(CHEMBL5196526)
Affinity DataKi:  4.00E+4nMAssay Description:Non competitive type inhibition of human TS assessed as inhibition constant using varying levels of mTHF as substrate by UV-Vis spectroscopy based an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetThymidylate synthase(Homo sapiens (Human))
University Of Modena And Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50590309(CHEMBL5196526)
Affinity DataKd:  4.40E+4nMAssay Description:Mixed type inhibition of human TS assessed as inhibitor dissociation constant by measuring changes in slope of the double reciprocal plot using dTMP ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed