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Found 3 Enz. Inhib. hit(s) with Target = 'Toll-like receptor 8' and Ligand = 'BDBM50514792'
TargetToll-like receptor 8(Homo sapiens (Human))
The University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM50514792(CHEMBL4519240)
Affinity DataIC50:  30nMAssay Description:Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of ssRNA06-induced NF-kappaB activation measured after 24 hrs by quanti-b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetToll-like receptor 8(Homo sapiens (Human))
The University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM50514792(CHEMBL4519240)
Affinity DataIC50:  30nMAssay Description:Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetToll-like receptor 8(Homo sapiens (Human))
The University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM50514792(CHEMBL4519240)
Affinity DataKd:  225nMAssay Description:Binding affinity to human TLR8 ectodomain by isothermal titration calorimetryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB