Found 5 Enz. Inhib. hit(s) with Target = 'Transcription initiation factor TFIID subunit 1' and Ligand = 'BDBM50503406' TargetTranscription initiation factor TFIID subunit 1(Homo sapiens (Human))
Genentech
Curated by ChEMBL
Genentech
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant His-tagged TAF1 bromodomain 2 (unknown origin) after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
3D Structure (crystal)TargetTranscription initiation factor TFIID subunit 1(Homo sapiens (Human))
Genentech
Curated by ChEMBL
Genentech
Curated by ChEMBL
Affinity DataIC50: 38nMAssay Description:Inhibition of fluorescent-tagged ligand from nanoLuc fused N-terminal TAF1 bromodomain 2 (unknown origin) expressed in 293T cells by luciferase repor...More data for this Ligand-Target Pair
TargetTranscription initiation factor TFIID subunit 1(Homo sapiens (Human))
Genentech
Curated by ChEMBL
Genentech
Curated by ChEMBL
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of recombinant His-tagged TAF1 bromodomain 1 (unknown origin) after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetTranscription initiation factor TFIID subunit 1(Homo sapiens (Human))
Genentech
Curated by ChEMBL
Genentech
Curated by ChEMBL
Affinity DataEC50: 920nMAssay Description:Binding affinity to TAF1 in HEK293T cells assessed as increase in TAF1 level by ITDR analysisMore data for this Ligand-Target Pair
TargetTranscription initiation factor TFIID subunit 1(Homo sapiens (Human))
Genentech
Curated by ChEMBL
Genentech
Curated by ChEMBL
Affinity DataKd: 39nMAssay Description:Binding affinity to human TAF1 tandem bromodomain (1373 to 1499 residues) transfected in Escherichia coli BL21 (DE3) assessed as dissociation constan...More data for this Ligand-Target Pair
