Found 3 Enz. Inhib. hit(s) with Target = 'Transient receptor potential cation channel subfamily M member 8' and Ligand = 'BDBM50420658' TargetTransient receptor potential cation channel subfamily M member 8(Rattus norvegicus (Rat))
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of rat TRPM8 expressed in HEK293 cells assessed as reduction in 0.25 uM icilin-stimulated increase in intracellular Ca2+ levelsMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily M member 8(Rattus norvegicus (Rat))
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of rat TRPM8 expressed in HEK293 cells assessed as reduction in 20 uM menthol-stimulated increase in intracellular Ca2+ levelsMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily M member 8(Rattus norvegicus (Rat))
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataEC50: 4.58E+4nMAssay Description:Activation of rat TRPM8 expressed in HEK293 cells assessed as stimulation of intracellular Ca2+ levelsMore data for this Ligand-Target Pair
