Compile Data Set for Download or QSAR
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Found 3 Enz. Inhib. hit(s) with Target = 'Transient receptor potential cation channel subfamily V member 1' and Ligand = 'BDBM20468'
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM20468(3-(2-bromophenyl)-1-{2-[ethyl(3-methylphenyl)amino...)
Affinity DataKi:  603nM ΔG°:  -35.5kJ/mole EC50:  95nMpH: 7.4 T: 2°CAssay Description:The hTRPV1-expressing CHO cell membranes were incubated with [3H]A-778317 and test compounds to establish equilibrium. After incubation was terminate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM20468(3-(2-bromophenyl)-1-{2-[ethyl(3-methylphenyl)amino...)
Affinity DataEC50:  16nMpH: 7.2 T: 2°CAssay Description:One day before the assay was performed, human TRPV1 expressed in 1321N1 astrocytoma cells were plated onto 96-well assay plates and grown until 2.5 h...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM20468(3-(2-bromophenyl)-1-{2-[ethyl(3-methylphenyl)amino...)
Affinity DataEC50:  16nMpH: 7.2 T: 2°CAssay Description:One day before the assay was performed, human TRPV1 expressed in 1321N1 astrocytoma cells were plated onto 96-well assay plates and grown until 2.5 h...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed