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Found 2 Enz. Inhib. hit(s) with Target = 'Transient receptor potential cation channel subfamily V member 4' and Ligand = 'BDBM50256212'
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50256212(CHEMBL4060956)
Affinity DataIC50:  0.620nMAssay Description:Antagonist activity at recombinant human TRPV4 expressed in CHOK1 cells assessed as inhibition of 4alphaPDD-induced activation pretreated for 5 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50256212(CHEMBL4060956)
Affinity DataIC50:  22nMAssay Description:Antagonist activity at recombinant rat TRPV4 expressed in CHOK1 cells assessed as inhibition of 4alphaPDD-induced activation pretreated for 5 mins fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed