Compile Data Set for Download or QSAR
maximum 50k data
Found 5 Enz. Inhib. hit(s) with Target = 'Transthyretin' and Ligand = 'BDBM50197885'
TargetTransthyretin(Homo sapiens (Human))
Albany College Of Pharmacy And Health Sciences

Curated by ChEMBL
LigandPNGBDBM50197885(CHEMBL3940890)
Affinity DataIC50:  160nMAssay Description:Binding affinity to human plasma TTR tetramer assessed as displacement of diclofenac-coupled FITC by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetTransthyretin(Homo sapiens (Human))
Albany College Of Pharmacy And Health Sciences

Curated by ChEMBL
LigandPNGBDBM50197885(CHEMBL3940890)
Affinity DataKd:  314nMAssay Description:Binding affinity to human plasma wild type TTR assessed as dissociation constants for first binding site of TTR by isothermal titration calorimetric ...More data for this Ligand-Target Pair
TargetTransthyretin(Homo sapiens (Human))
Albany College Of Pharmacy And Health Sciences

Curated by ChEMBL
LigandPNGBDBM50197885(CHEMBL3940890)
Affinity DataKd:  7.30nMAssay Description:Binding affinity to human TTR incubated for 20 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetTransthyretin(Homo sapiens (Human))
Albany College Of Pharmacy And Health Sciences

Curated by ChEMBL
LigandPNGBDBM50197885(CHEMBL3940890)
Affinity DataKd:  4.80nMAssay Description:Binding affinity to human plasma wild type TTR assessed as dissociation constants for second binding site of TTR by isothermal titration calorimetric...More data for this Ligand-Target Pair
TargetTransthyretin(Homo sapiens (Human))
Albany College Of Pharmacy And Health Sciences

Curated by ChEMBL
LigandPNGBDBM50197885(CHEMBL3940890)
Affinity DataKd:  4.80nMAssay Description:Binding affinity to transthyretin (unknown origin) by ITC methodMore data for this Ligand-Target Pair