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Found 1 Enz. Inhib. hit(s) with Target = 'Tryptophan 2,3-dioxygenase' and Ligand = 'BDBM514558'
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM514558(6,6-dimethyl-3-phenyl-8-(7- (trifluoromethyl)imida...)
Affinity DataIC50:  3.80E+4nMAssay Description:Recombinant human IDO or TDO was incubated in 50 mM KPO4 (pH 7.0), 0.5 mM EGTA, 0.5 mM EDTA, 0.05% Triton™ X100, 20 mM ascorbate, 10 μM methylen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent