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Found 30 Enz. Inhib. hit(s) with Target = 'Type-1 angiotensin II receptor' and Ligand = 'BDBM50009714'
TargetType-1 angiotensin II receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50009714(CHEMBL191 | {2-Butyl-5-chloro-3-[2'-(2H-tetrazol-5...)
Affinity DataIC50:  8nMAssay Description:Tested for inhibition of Angiotensin II receptor, type 1 in the absence of bovine serum albumin (BSA)More data for this Ligand-Target Pair
In DepthDetails Article
TargetType-1 angiotensin II receptor(RABBIT)
Università

Curated by ChEMBL
LigandPNGBDBM50009714(CHEMBL191 | {2-Butyl-5-chloro-3-[2'-(2H-tetrazol-5...)
Affinity DataIC50:  10nMAssay Description:Antagonist activity against AT1 receptor assessed as inhibition of Ang2-induced rabit aortic strip contractionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(Cavia porcellus)
TBA

Curated by ChEMBL
LigandPNGBDBM50009714(CHEMBL191 | {2-Butyl-5-chloro-3-[2'-(2H-tetrazol-5...)
Affinity DataIC50:  18nMAssay Description:Compound was tested for in vitro inhibition of specific binding of [I-125]AII to Angiotensin II receptor, type 1 in guinea pig adrenal membrane prepa...More data for this Ligand-Target Pair
In DepthDetails Article
TargetType-1 angiotensin II receptor(Cavia porcellus)
TBA

Curated by ChEMBL
LigandPNGBDBM50009714(CHEMBL191 | {2-Butyl-5-chloro-3-[2'-(2H-tetrazol-5...)
Affinity DataIC50:  18nMAssay Description:Inhibition of [125I]-Angiotensin binding to a guinea pig adrenal membrane preparation which corresponds to Angiotensin II receptor, type 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(RABBIT)
Università

Curated by ChEMBL
LigandPNGBDBM50009714(CHEMBL191 | {2-Butyl-5-chloro-3-[2'-(2H-tetrazol-5...)
Affinity DataIC50:  19nMAssay Description:In vitro antagonistic activity for AT1 receptor by displacing 125I[Sar, ILe8]AII radioligand in rabbit aorta membrane using 0.2% bovine serum albumin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50009714(CHEMBL191 | {2-Butyl-5-chloro-3-[2'-(2H-tetrazol-5...)
Affinity DataIC50:  28nMAssay Description:Inhibition of the compound against human angiotensin II receptor, type 1 (AG2-R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(RABBIT)
Università

Curated by ChEMBL
LigandPNGBDBM50009714(CHEMBL191 | {2-Butyl-5-chloro-3-[2'-(2H-tetrazol-5...)
Affinity DataIC50:  30nMAssay Description:In vitro inhibitory activity against Angiotensin II receptor, type 1 in rabbit aorta membrane preparations.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50009714(CHEMBL191 | {2-Butyl-5-chloro-3-[2'-(2H-tetrazol-5...)
Affinity DataIC50:  30nMAssay Description:In vitro inhibitory activity against Angiotensin II receptor, type 1 in rabbit aorta membrane preparations.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(RABBIT)
Università

Curated by ChEMBL
LigandPNGBDBM50009714(CHEMBL191 | {2-Butyl-5-chloro-3-[2'-(2H-tetrazol-5...)
Affinity DataIC50:  40nMAssay Description:In vitro inhibitory activity against angiotensin II rabbit aorta AT1 receptor using radioligand [125I]-Sar Ile-AIIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(RABBIT)
Università

Curated by ChEMBL
LigandPNGBDBM50009714(CHEMBL191 | {2-Butyl-5-chloro-3-[2'-(2H-tetrazol-5...)
Affinity DataIC50:  40nMAssay Description:Evaluation of Angiotensin II antagonistic activity by displacement of [125I]-Sar Ile-AII at the rabbit aorta Angiotensin II receptor, type 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(RABBIT)
Università

Curated by ChEMBL
LigandPNGBDBM50009714(CHEMBL191 | {2-Butyl-5-chloro-3-[2'-(2H-tetrazol-5...)
Affinity DataIC50:  50nMAssay Description:Displacement of [125I]-Sar1-Ile8-A II at the rabbit aorta angiotensin II receptor, type 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(RABBIT)
Università

Curated by ChEMBL
LigandPNGBDBM50009714(CHEMBL191 | {2-Butyl-5-chloro-3-[2'-(2H-tetrazol-5...)
Affinity DataIC50:  50nMAssay Description:In vitro antagonistic activity for angiotensin II receptor, type 1 by displacing 125I[Sar, ILe8 ]AII radioligand in rabbit aorta membrane without usi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(RABBIT)
Università

Curated by ChEMBL
LigandPNGBDBM50009714(CHEMBL191 | {2-Butyl-5-chloro-3-[2'-(2H-tetrazol-5...)
Affinity DataIC50:  50nMAssay Description:In vitro binding affinity of the compound for angiotensin II AT1 receptor in rabbit aortaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(RABBIT)
Università

Curated by ChEMBL
LigandPNGBDBM50009714(CHEMBL191 | {2-Butyl-5-chloro-3-[2'-(2H-tetrazol-5...)
Affinity DataIC50:  54nMAssay Description:In vitro antagonist activity against angiotensin II receptor type 1 in rabbit aorta using [125I]-Sar, Ile AII.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(RABBIT)
Università

Curated by ChEMBL
LigandPNGBDBM50009714(CHEMBL191 | {2-Butyl-5-chloro-3-[2'-(2H-tetrazol-5...)
Affinity DataIC50:  54nMAssay Description:In vitro antagonist activity against angiotensin II receptor type 1 in rabbit aorta using [125I]-Sar, Ile AII.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(RABBIT)
Università

Curated by ChEMBL
LigandPNGBDBM50009714(CHEMBL191 | {2-Butyl-5-chloro-3-[2'-(2H-tetrazol-5...)
Affinity DataIC50:  54nMAssay Description:Displacement of [1251][Sar1,IIe8]AII from rabbit aorta Angiotensin II receptor, type 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(Bos taurus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50009714(CHEMBL191 | {2-Butyl-5-chloro-3-[2'-(2H-tetrazol-5...)
Affinity DataIC50:  120nMAssay Description:Displacement of [125I]angiotensin-2 from bovine adrenal cortex AT1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(Bos taurus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50009714(CHEMBL191 | {2-Butyl-5-chloro-3-[2'-(2H-tetrazol-5...)
Affinity DataIC50:  120nMAssay Description:In vitro for inhibition of [125I]-angiotensin II (0.1 nM) binding to angiotensin II receptor type 1 in membrane fractions of bovine adrenal cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(Bos taurus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50009714(CHEMBL191 | {2-Butyl-5-chloro-3-[2'-(2H-tetrazol-5...)
Affinity DataIC50:  120nMAssay Description:Inhibition of [125l]-All binding to bovine adrenal cortexMore data for this Ligand-Target Pair
In DepthDetails Article
TargetType-1 angiotensin II receptor(Bos taurus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50009714(CHEMBL191 | {2-Butyl-5-chloro-3-[2'-(2H-tetrazol-5...)
Affinity DataIC50:  150nMAssay Description:Displacement of [125 I]-AII (0.2 nM) from bovine adrenal cortical membrane angiotensin II (AII) receptor at 10e-7 MMore data for this Ligand-Target Pair
In DepthDetails Article
TargetType-1 angiotensin II receptor(Bos taurus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50009714(CHEMBL191 | {2-Butyl-5-chloro-3-[2'-(2H-tetrazol-5...)
Affinity DataIC50:  160nMAssay Description:Tested for binding affinity against angiotensin II receptor in bovine adrenal cortexMore data for this Ligand-Target Pair
In DepthDetails Article
TargetType-1 angiotensin II receptor(Bos taurus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50009714(CHEMBL191 | {2-Butyl-5-chloro-3-[2'-(2H-tetrazol-5...)
Affinity DataIC50:  160nMAssay Description:Displacement of [125I]Ang2 from AT1 receptor in bovine adrenal cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(Bos taurus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50009714(CHEMBL191 | {2-Butyl-5-chloro-3-[2'-(2H-tetrazol-5...)
Affinity DataIC50:  300nMAssay Description:Binding affinity for angiotensin II receptor of bovine adrenal cortexMore data for this Ligand-Target Pair
In DepthDetails Article
TargetType-1 angiotensin II receptor(Bos taurus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50009714(CHEMBL191 | {2-Butyl-5-chloro-3-[2'-(2H-tetrazol-5...)
Affinity DataIC50:  330nMAssay Description:In vitro Angiotensin II receptor antagonism in bovine adrenal cortex tissue.More data for this Ligand-Target Pair
In DepthDetails Article
TargetType-1 angiotensin II receptor(Bos taurus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50009714(CHEMBL191 | {2-Butyl-5-chloro-3-[2'-(2H-tetrazol-5...)
Affinity DataIC50:  330nMAssay Description:Binding affinity of the compound expressed as inhibitory concentration towards bovine adrenal cortex angiotensin II receptor was measuredMore data for this Ligand-Target Pair
In DepthDetails Article
TargetType-1 angiotensin II receptor(Bos taurus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50009714(CHEMBL191 | {2-Butyl-5-chloro-3-[2'-(2H-tetrazol-5...)
Affinity DataIC50:  330nMAssay Description:In vitro binding affinity to angiotensin II receptor in bovine adrenal cortexMore data for this Ligand-Target Pair
In DepthDetails Article
TargetType-1 angiotensin II receptor(Bos taurus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50009714(CHEMBL191 | {2-Butyl-5-chloro-3-[2'-(2H-tetrazol-5...)
Affinity DataIC50:  420nMAssay Description:Ability of the compound to displace [125I]- labelled [Sar1,Ileu8] from angiotensin II receptor of bovine adrenal cortex membranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetType-1 angiotensin II receptor(Bos taurus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50009714(CHEMBL191 | {2-Butyl-5-chloro-3-[2'-(2H-tetrazol-5...)
Affinity DataIC50:  425nMAssay Description:Concentration that gives 50% inhibition for binding of 125-I-[Sar1, IIe8] angiotensin to Angiotensin II receptor, type 1 in bovine adrenal cortex mem...More data for this Ligand-Target Pair
In DepthDetails Article
TargetType-1 angiotensin II receptor(Bos taurus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50009714(CHEMBL191 | {2-Butyl-5-chloro-3-[2'-(2H-tetrazol-5...)
Affinity DataIC50:  3.30E+5nMAssay Description:Concentration required for 50% inhibition of binding against Angiotensin II receptor in the bovine adrenal cortex tissueMore data for this Ligand-Target Pair
In DepthDetails Article
TargetType-1 angiotensin II receptor(Bos taurus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50009714(CHEMBL191 | {2-Butyl-5-chloro-3-[2'-(2H-tetrazol-5...)
Affinity DataEC50:  350nMAssay Description:Inhibition of [125I]-AII binding to angiotensin II receptor of bovine adrenal cortexMore data for this Ligand-Target Pair
In DepthDetails Article