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Found 2 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase ABL1 [64-515]' and Ligand = 'BDBM230817'
TargetTyrosine-protein kinase ABL1 [64-515](Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM230817(US9340537, 71 | US9896444, Example 71)
Affinity DataIC50:  0.400nMAssay Description:Caliper ABL1 (64-515) Assay: The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase ABL1 [64-515](Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM230817(US9340537, 71 | US9896444, Example 71)
Affinity DataIC50:  0.400nMpH: 7.5 T: 2°CAssay Description:The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent