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Found 2 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase ABL1 [Y253F]' and Ligand = 'BDBM332706'
TargetTyrosine-protein kinase ABL1 [Y253F](Homo sapiens (Human))
The Regents of The University of Michigan

US Patent
LigandPNGBDBM332706(US10196378, Compound C09 | US10196378, Compound C1...)
Affinity DataKi:  2.5nMAssay Description:The biochemical assays were carried out using the non-phosphorylated kinase domain of c-Abl, Bcr-Abl in Ba/F3 cells is in the phosphorylated state.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase ABL1 [Y253F](Homo sapiens (Human))
The Regents of The University of Michigan

US Patent
LigandPNGBDBM332706(US10196378, Compound C09 | US10196378, Compound C1...)
Affinity DataKi:  7.60nMAssay Description:The biochemical assays were carried out using the non-phosphorylated kinase domain of c-Abl, Bcr-Abl in Ba/F3 cells is in the phosphorylated state.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent