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Found
1
Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase BTK' and Ligand = 'BDBM267553'
Target
Tyrosine-protein kinase BTK
(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Ligand
BDBM267553
((R)-4-(8-amino-3-(1-ethylpiperidin-3-yl)imidazo[1,...)
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Affinity Data
EC50: <10nM
pH: 7.2 T: 2°C
Assay Description:
Btk enzyme activity is measured using the IMAP (immobilized metal ion affinity-based fluorescence polarization) assay as outlined below. Btk enzyme (...
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Ligand Info
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