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Found 2 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase BTK' and Ligand = 'BDBM267958'
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM267958(4-[8-amino-3-(1-ethyl-2-oxopiperidin-4-yl)imidazo[...)
Affinity DataIC50:  5.30nMAssay Description:Inhibition of recombinant full-length His6-tagged BTK (unknown origin) expressed in baculovirus infected Sf9 cells using biotinylated A5 peptide as s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM267958(4-[8-amino-3-(1-ethyl-2-oxopiperidin-4-yl)imidazo[...)
Affinity DataIC50: <10nMpH: 7.2Assay Description:BTK enzymatic activity was determined in an IMAP-FP assay (Immobilized Metal ion Affinity-based fluorescence Polarization; Molecular Devices). Using ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent