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Found 2 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase BTK' and Ligand = 'BDBM295019'
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Centaurus Biopharma

US Patent
LigandPNGBDBM295019(US10112922, Compound 9)
Affinity DataIC50:  1.90nMAssay Description:In vitro activity in inhibiting ITK kinase was determined similar to that in respect of BTK kinase.The inhibitory activity of the compound of Example...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Centaurus Biopharma

US Patent
LigandPNGBDBM295019(US10112922, Compound 9)
Affinity DataIC50: <100nMpH: 7.4Assay Description:The half inhibition concentrations (IC50 values) of the compounds disclosed herein on Btk were determined at both enzymatic level and cellular level:...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent