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Found 2 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase BTK' and Ligand = 'BDBM359058'
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM359058((6R,8aS)-6-[8-amino-5- chloro-1-(2-fluoro-4- {1-hy...)
Affinity DataIC50:  1.20nMAssay Description:BTK enzymatic activity was determined with the LANCE (Lanthanide Chelate Excite) TR-FRET (Time-resolved fluorescence resonance energy transfer) assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM359058((6R,8aS)-6-[8-amino-5- chloro-1-(2-fluoro-4- {1-hy...)
Affinity DataIC50:  310nMAssay Description:BTK enzymatic activity was determined with the LANCE (Lanthanide Chelate Excite) TR-FRET (Time-resolved fluorescence resonance energy transfer) assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent