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Found 2 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase BTK' and Ligand = 'BDBM499829'
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Arqule

US Patent
LigandPNGBDBM499829((4-((cis-4-aminocyclohexyl)amino)-7H- pyrrolo[2,3-...)
Affinity DataIC50:  2.20nMAssay Description:Full length unphosphorylated form of BTK expressed in Sf9 cells was employed to test inhibitory activity in the inactive BTK assay. The assay was mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Arqule

US Patent
LigandPNGBDBM499829((4-((cis-4-aminocyclohexyl)amino)-7H- pyrrolo[2,3-...)
Affinity DataIC50:  4.30nMAssay Description:Inhibition of full length N-terminal GST fusion tagged human BTK expressed in baculovirus expression system using FAM-P2 peptide solution as substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed