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Found 6 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase BTK' and Ligand = 'BDBM50276666'
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
University Of Science And Technology Of China

Curated by ChEMBL
LigandPNGBDBM50276666(CHEMBL4166664)
Affinity DataKi:  97nMAssay Description:Inhibition of recombinant full length His-tagged human BTK expressed in baculovirus expression system using poly (4:1 Glu, Tyr) as substrate preincub...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
University Of Science And Technology Of China

Curated by ChEMBL
LigandPNGBDBM50276666(CHEMBL4166664)
Affinity DataIC50:  76nMAssay Description:Inhibition of recombinant full length His-tagged human BTK expressed in baculovirus expression system using poly (4:1 Glu, Tyr) as substrate preincub...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
University Of Science And Technology Of China

Curated by ChEMBL
LigandPNGBDBM50276666(CHEMBL4166664)
Affinity DataEC50: <3.00E+3nMAssay Description:Inhibition of recombinant full length His-tagged human BTK expressed in baculovirus expression system using poly (4:1 Glu, Tyr) as substrate preincub...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
University Of Science And Technology Of China

Curated by ChEMBL
LigandPNGBDBM50276666(CHEMBL4166664)
Affinity DataEC50: <1.00E+3nMAssay Description:Inhibition of BTK autophosphorylation at Y223 in anti-IgM stimulated human MOLM13 cells after 4 hrs by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
University Of Science And Technology Of China

Curated by ChEMBL
LigandPNGBDBM50276666(CHEMBL4166664)
Affinity DataEC50: <100nMAssay Description:Inhibition of recombinant full length His-tagged human BTK expressed in baculovirus expression system using poly (4:1 Glu, Tyr) as substrate preincub...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
University Of Science And Technology Of China

Curated by ChEMBL
LigandPNGBDBM50276666(CHEMBL4166664)
Affinity DataEC50: <100nMAssay Description:Inhibition of BTK autophosphorylation at Y223 in anti-IgM stimulated human Ramos cells after 4 hrs by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed