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Found 2 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase BTK [C481S]' and Ligand = 'BDBM499811'
TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Arqule

US Patent
LigandPNGBDBM499811(US11020398, Compound I-123 | US20230364079, Exampl...)
Affinity DataIC50:  0.390nMAssay Description:Enzyme assay using full length recombinant active form of wild-type BTK and BTK-C481S was measured as described previously (Anastassiadis T, et al., ...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Arqule

US Patent
LigandPNGBDBM499811(US11020398, Compound I-123 | US20230364079, Exampl...)
Affinity DataIC50: <5nMAssay Description:Kinase Reaction Process: (1) Preparation of 1 × Kinase buffer.(2) Preparation of compound with gradient concentrations: The test compound was tested ...More data for this Ligand-Target Pair