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Found 4 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK1' and Ligand = 'BDBM103728'
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM103728(US10206907, Compound 18 | US11000528, Cpd # 2 | US...)
Affinity DataIC50:  50.9nMAssay Description:In vitro inhibition assay using various enzyme.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM103728(US10206907, Compound 18 | US11000528, Cpd # 2 | US...)
Affinity DataIC50:  52.1nMAssay Description:In vitro inhibition assay using various enzyme.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM103728(US10206907, Compound 18 | US11000528, Cpd # 2 | US...)
Affinity DataIC50:  92nMAssay Description:Inhibition of human recombinant JAK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM103728(US10206907, Compound 18 | US11000528, Cpd # 2 | US...)
Affinity DataIC50:  5.59E+3nMAssay Description:Inhibition of JAK1 in human whole blood assessed as inhibition of IL-6-induced pSTAT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed