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Found 3 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK1' and Ligand = 'BDBM50545650'
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Japan Tobacco

Curated by ChEMBL
LigandPNGBDBM50545650(Delgocitinib | JTE-052 | JTE-052A | LEO 124249 | L...)
Affinity DataIC50:  2.80nMAssay Description:Inhibition of N-terminal GST-fused human JAK1 (850 to 1154 residues) expressed in baculovirus expression system using TK-substrate-biotin as substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Japan Tobacco

Curated by ChEMBL
LigandPNGBDBM50545650(Delgocitinib | JTE-052 | JTE-052A | LEO 124249 | L...)
Affinity DataIC50:  2.80nMAssay Description:Inhibition of recombinant human JAK1 (850 to end residues) in the presence of [gamma p33]-ATPMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Japan Tobacco

Curated by ChEMBL
LigandPNGBDBM50545650(Delgocitinib | JTE-052 | JTE-052A | LEO 124249 | L...)
Affinity DataIC50:  2.80nMAssay Description:Inhibition of JAK 1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed