TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Shanghai Longwood Biopharmaceuticals
US Patent
Shanghai Longwood Biopharmaceuticals
US Patent
Affinity DataIC50: 0.720nMAssay Description:Kinase Assay:Preparation of buffers, the buffer included 50 mM HEPES (pH 7.5), 0.01% Brij-35, 10 mM MgCl2, and 1 mM EGTA.After the buffer was formula...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Shanghai Longwood Biopharmaceuticals
US Patent
Shanghai Longwood Biopharmaceuticals
US Patent
Affinity DataIC50: 3nMAssay Description:Test method: Firstly, test compounds were prepared into 10 mM stock solution with DMSO, and continuously diluted into 10 concentrations at a 3-fold g...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Shanghai Longwood Biopharmaceuticals
US Patent
Shanghai Longwood Biopharmaceuticals
US Patent
Affinity DataIC50: 3.5nMAssay Description:JAK3 and BTK kinases inhibitory activities were measured for the compounds prepared in the Examples through in vitro analysis on the ADP Glow (Glo) p...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Shanghai Longwood Biopharmaceuticals
US Patent
Shanghai Longwood Biopharmaceuticals
US Patent
Affinity DataIC50: <20nMAssay Description:The study of the effect of compounds on the activity of purified recombinant JAK was performed by studying the inhibitory activity of the compounds o...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Shanghai Longwood Biopharmaceuticals
US Patent
Shanghai Longwood Biopharmaceuticals
US Patent
Affinity DataIC50: 474nMAssay Description:Test method: Firstly, test compounds were prepared into 10 mM stock solution with DMSO, and continuously diluted into 10 concentrations at a 3-fold g...More data for this Ligand-Target Pair