Compile Data Set for Download or QSAR
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Found 3 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein phosphatase non-receptor type 1' and Ligand = 'BDBM50133281'
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50133281(5-(4-Bromo-phenyl)-isoxazole-3-carboxylic acid | C...)
Affinity DataKd:  8.00E+5nMAssay Description:Dissociation constant of the compound against Protein-tyrosine phosphatase 1B receptor was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50133281(5-(4-Bromo-phenyl)-isoxazole-3-carboxylic acid | C...)
Affinity DataKd:  8.00E+5nMAssay Description:Binding affinity to N-terminal GST-fused human PTP1B (1 to 288 residues) expressed in Escherichia coli BL21(DE3) by HSQC NMR analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50133281(5-(4-Bromo-phenyl)-isoxazole-3-carboxylic acid | C...)
Affinity DataKd:  8.00E+5nMAssay Description:Dissociation constant for Protein-tyrosine phosphatase 1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed