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Found 3 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein phosphatase non-receptor type 6' and Ligand = 'BDBM50087879'
LigandPNGBDBM50087879(CHEMBL472004 | NSC-87877)
Affinity DataIC50:  0.335nMAssay Description:Inhibition of SHP1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50087879(CHEMBL472004 | NSC-87877)
Affinity DataIC50:  355nMAssay Description:Inhibition of recombinant GST-fused human SHP1 (205 to 597 residues) using DiFMUP as substrate incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50087879(CHEMBL472004 | NSC-87877)
Affinity DataIC50:  360nMAssay Description:Inhibition of human SHP1 catalytic domain (205 to 597 residues) expressed in Escherichia coli DH5alpha using 6,8-difluoro-4-methylumbelliferyl phosph...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed