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Found 1 Enz. Inhib. hit(s) with Target = 'Tyrosyl-DNA phosphodiesterase 1' and Ligand = 'BDBM4301'
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM4301((2E)-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enamide...)
Affinity DataIC50: >3.33E+5nMAssay Description:Inhibition of human recombinant Tdp1 assessed as conversion of 14-mer 5'-32P-labeled 3'-phosphotyrosyl DNA substrate N14Y to 14-mer 5'-32P-labeled 3'...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed