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Found
1
Enz. Inhib. hit(s) with Target = 'Tyrosyl-DNA phosphodiesterase 1' and Ligand = 'BDBM4301'
Target
Tyrosyl-DNA phosphodiesterase 1
(Homo sapiens (Human))
University Of Minnesota
Curated by
ChEMBL
Ligand
BDBM4301
((2E)-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enamide...)
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Affinity Data
IC50: >3.33E+5nM
Assay Description:
Inhibition of human recombinant Tdp1 assessed as conversion of 14-mer 5'-32P-labeled 3'-phosphotyrosyl DNA substrate N14Y to 14-mer 5'-32P-labeled 3'...
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Target Info
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