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Found 4 Enz. Inhib. hit(s) with Target = 'Ubiquitin carboxyl-terminal hydrolase 7' and Ligand = 'BDBM50250952'
TargetUbiquitin carboxyl-terminal hydrolase 7(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50250952(CHEMBL4065700)
Affinity DataIC50:  5.20E+3nMAssay Description:Inhibition of native full length C-terminal USP7 (unknown origin) using ubiquitin-Rho110 as substrate pre-incubated for 1 hr followed by substrate ad...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUbiquitin carboxyl-terminal hydrolase 7(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50250952(CHEMBL4065700)
Affinity DataIC50:  5.20E+3nMAssay Description:Inhibition of human USP7 using UbA10 as substrate incubated for 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetUbiquitin carboxyl-terminal hydrolase 7(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50250952(CHEMBL4065700)
Affinity DataIC50:  9.90E+3nMAssay Description:Inhibition of human USP7 using ubiquitin-Rho as substrate incubated for 1 hrsMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetUbiquitin carboxyl-terminal hydrolase 7(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50250952(CHEMBL4065700)
Affinity DataEC50:  3.75E+4nMAssay Description:Inhibition of CYP2A6 in human liver microsomes preincubated for 5 mins followed by addition of NADPH generating system measured after 20 mins by LC-M...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed